Feng LIU

Address: School of Physics, Nanjing University, Nanjing, 210093, China

Tel: +86 25 83598556

Email: fliu(at)nju(dot)edu(dot)cn



 

Education
B. S. Nanjing University 1993
M. S. Nanjing University 1996
Ph. D. Nanjing University 1998

 

Positions

2006.12 - present Professor Department of Physics, Nanjing University
2001.4 - 2006.11 Associate Professor Department of Physics, Nanjing University
1999.4 - 2001.3  Lecturer Department of Physics, Nanjing University
     
2012.1 - 2017.12 Associate Member The Abdus Salam International Centre for Theoretical Physics (ICTP, Italy)
2003.10 - 2005.9  Post-doctoral Fellow Department of Physics, Brandeis University (USA)
2001.4 - 2001.9 Visiting Scholar COGS, University of Sussex (UK)

Research interests
Systems Biology: Dynamics of cellular singaling networks and gene transcription
Computational Neuroscience:

Cortical dynamics (perceptual decsion making and working memory)

 

Selected publications

1. X. Tian, B. Huang, X.-P. Zhang, M. Lu, F. Liu, J.N. Onuchic and W. Wang (2017) Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals. Proc. Natl. Acad. Sci. USA 114, 5337-5342.

2. Y. Wang, F. Liu, and W. Wang (2016) Kinetics of transcription initiation directed by multiple cis-regulatory elements on the glnAp2 promoter. Nucleic Acids Res. 44, 10530-10538.

3. C. Xue and F. Liu (2014) Structured  synaptic inhibition has a critical role in multiple-choice motion-discrimination tasks. J. Neurosci. 34, 13444-13457.

4. X.-P. Zhang, F. Liu, and W. Wang (2011) Two-phase dynamics of p53 in the DNA damage response. Proc. Natl. Acad. Sci. USA 108, 8990-8995. 

5. X.-P. Zhang, F. Liu, Z. Cheng, and W. Wang (2009) Cell fate decision mediated by p53 pulses. Proc. Natl. Acad. Sci. USA 106, 12245-12250. 

6. F. Liu and X.-J. Wang (2008) A common cortical circuit mechanism for perceptual categorical discrimination and veridical judgment. PLoS Comput. Biol. 4, e1000253: 1-14. 

7. B. Huang, X. Tian, F. Liu, and W. Wang (2016) Impact of time delays on oscillatory dynamics of interlinked positive and negative feedback loops. Phys. Rev. E 94, 052413: 1-12.

8. B. Huang, Y. Xia, F. Liu, and W. Wang (2016) Realization of tristability in a multiplicatively coupled dual-loop genetic network. Sci. Rep.  6, 28096.

9. C.-H. Zhou, X.-P. Zhang, F. Liu, and W. Wang (2015) Modeling the interplay between the HIF-1 and p53 pathways in hypoxia. Sci. Rep. 5, 13834.

10. X.-P. Zhang, F. Liu, and W. Wang (2014) Nonlinear dynamics in the p53 signaling network (in Chinese). Sci. Sin.-Phys. Mech. Astron. 44, 1311C1318.

11. Q.H. Zhang, X.J. Tian, F. Liu and W. Wang (2014) A switch-like dynamic mechanism for the initiation of replicative senescence. FEBS Lett. 588, 4369-4374.

12. Y. Wang, F. Liu, J. Li and W. Wang (2014) Reconciling the concurrent fast and slow cycling of proteins on gene promoters. J. R. Soc. Interface 11, 20140253.

13. X.-P. Zhang, F. Liu and W. Wang (2014) Interplay between Mdm2 and HIPK2 in the DNA damage response. J. R. Soc. Interface 11, 20140319.

14. C.-H. Zhou, X.-P. Zhang, F. Liu, and W. Wang (2014) Involvement of miR-605 and miR-34a in the DNA damage response promotes apoptosis induction. Biophys. J. 106, 1792-1800.

15. Y. Wang, F. Liu and W. Wang (2012) Dynamic mechanism for the transcription apparatus orchestrating reliable responses to activators. Sci. Rep. 2, 422. 

16. X.-P. Zhang, F. Liu and W. Wang (2012) Regulation of the DNA damage response by p53 cofactors. Biophys. J. 102, 2251-2260.

17. X.-J. Tian, F. Liu, X.-P. Zhang, J. Li and W. Wang (2012) A two-step mechanism for cell fate decision by coordination of nuclear and mitochondrial p53 activities.  PLoS ONE 7, e38164. 

18. X.-P. Zhang, F. Liu and W. Wang (2010) Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in  response to DNA damage.  J. Biol. Chem. 285, 31571-31580. 

19. T. Pu, X.-P. Zhang, F. Liu and W. Wang (2010) Coordination of the nuclear and cytoplasmic activities of p53 in response to DNA damage. Biophys. J. 99,1696-1705.  

20. Z. Cheng, F. Liu, X.-P. Zhang and W. Wang (2009) Reversible phosphorylation subserves robust circadian rhythms by creating a switch in inactivating the positive element. Biophys. J. 97, 2867-2875.  

21. J. Li, F. Liu, D. Xu and W. Wang (2009) Signal Propagation through feedforward neuronal networks with different operational modes. EPL 85, 38006: 1-6. 

22. S.T. Wang, W. Wang and F. Liu (2006) Propagation of firing rate in a feed-forward neuronal network. Phys. Rev. Lett. 96, 018103: 1-4. 

23. Z. Cheng, F. Liu, X.-P. Zhang and W. Wang (2008) Robustness analysis of cellular memory in an autoactivating positive feedback system. FEBS Lett. 582, 3776-3782. 

24. X.-J. Tian, X.-P. Zhang, F. Liu and W. Wang (2009) Interlinking positive and negative feedback loops creates a tunable motif in gene regulatory networks. Phys. Rev. E 80, 011926: 1-8. 

25. X.-P. Zhang, Z. Cheng, F. Liu and W. Wang (2007) Linking fast and slow positive feedback loops creates an optimal bistable switch in cell signaling. Phys. Rev. E 76, 031924: 1-8. 

 

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