Feng LIU

Address: School of Physics, Nanjing University, Nanjing, 210093, China

Tel: +86 25 83598556

Email: fliu(at)nju(dot)edu(dot)cn 　

Education

Positions

Research interests

Selected publications

P. Wang, X.-P. Zhang^*, F. Liu^* and W. Wang^* (2025) Progressive deactivation of hydroxylases controls hypoxia-inducible factor-1α-coordinated cellular adaptation to graded hypoxia. Research 8, 0651.

R. Wu, B. Zhou, W. Wang^* and F. Liu^* (2023) Regulatory mechanisms for transcriptional bursting revealed by an event-based model. Research 6, 0253.   

Y. Wang, T. Ni, W. Wang^* and F. Liu^* (2019) Gene transcription in bursting: A unified mode for realizing accuracy and stochasticity.  Biol. Rev. 94, 248-258.

R. Yang⁺, B. Huang⁺, Y. Zhu, Y. Li, F. Liu^* and J. Shi^* (2018) Cell type-dependent bimodal p53 activation engenders a dynamic mechanism of chemoresistance.  Sci. Adv. 4, eaat5077.

X. Tian⁺, B. Huang⁺, X.-P. Zhang, M. Lu, F. Liu^*, J.N. Onuchic^* and W. Wang^* (2017) Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals.  Proc. Natl. Acad. Sci. USA 114, 5337-5342.

Y. Wang, F. Liu^* and W. Wang^* (2016) Kinetics of transcription initiation directed by multiple cis-regulatory elements on the glnAp2 promoter.  Nucleic Acids Res. 44, 10530-10538. 

C. Xue and F. Liu^* (2014) Structured synaptic inhibition has a critical role in multiple-choice motion-discrimination tasks.  J. Neurosci. 34, 13444-13457.

X.-P. Zhang, F. Liu^* and W. Wang^* (2011) Two-phase dynamics of p53 in the DNA damage response.  Proc. Natl. Acad. Sci. USA 108, 8990-8995. 

X.-P. Zhang, F. Liu^*, Z. Cheng and W. Wang^* (2009) Cell fate decision mediated by p53 pulses.  Proc. Natl. Acad. Sci. USA 106, 12245-12250.

F. Liu and X.-J. Wang^* (2008) A common cortical circuit mechanism for perceptual categorical discrimination and veridical judgment.  PLoS Comput. Biol. 4, e1000253. 

T.  Wang, J.-X. Gui, M. Zuo, W. Wang* and F. Liu* (2025) Self-sustained and oscillatory activity in two types of attractor networks. Nonlinear Dyn. 113, 15421-15439. 

H.-Y. Wang, K. Yu, Z. Yang, G. Zhang, S.-Q. Guo, T. Wang, D.-D. Liu, R.-N. Jia, Y.-T. Zheng, Y.-N. Su, Y. Lou, K. R. Weiss, H.-B. Zhou^*, F. Liu^*, E. C. Cropper, Q. Yu^* and J. Jing^* (2023) A single central pattern generator for the control of a locomotor rolling wave in Mollusc Aplysia.  Research 6, 0060.

Z. Wang, T. Wang, F. Yang, F. Liu^* and W. Wang^* (2023) Intrinsic theta oscillation in the attractor network of grid cells.  iScience 26, 106351.

Y. Zhou and F. Liu^* (2022) Coordination of the AMPK, Akt, mTOR, and p53 pathways under glucose starvation.  Int. J. Mol. Sci. 23, 14945.

T. Wang, F. Yang, Z. Wang, B. Zhang^*, W. Wang^* and F. Liu^* (2021) Modularization of grid cells constrained by the pyramidal patch lattice.  iScience 24, 102301.

T. Wang, J. Sun, F. Yang, J. Li^*, W. Wang and F. Liu^* (2021) Background synaptic input modulates the visuospatial working memory.  Phys. Rev. E 104, 024416.

C.-Y. Sun, X.-P. Zhang^*, F. Liu^* and W. Wang (2020) Orchestration of lincRNA-p21 and miR-155 in modulating the adaptive dynamics of HIF-1α.  Front. Genet. 11, 871.

P. Wang, D. Guan, X.-P. Zhang^*, F. Liu^* and W. Wang^* (2019) Modeling the regulation of p53 activation by HIF-1 upon hypoxia.  FEBS Lett. 593, 2596-2611.

D.-G. Wang, S. Wang, B. Huang^* and F. Liu^* (2019) Roles of cellular heterogeneity, intrinsic and extrinsic noise in variability of p53 oscillation.  Sci. Rep. 9, 5883.

P. Wang, H. Bao, X.-P. Zhang^*, F. Liu^* and W. Wang (2019) Regulation of Tip60-dependent p53 acetylation in cell fate decision.  FEBS Lett. 593, 13-22.

Y. Xia, Z. Cheng, S. Wang, D. Guan and F. Liu^* (2018) Modeling the crosstalk between the circadian clock and ROS in Neurospora crassa.  J. Theor. Biol. 458, 125-132.

L.S. Wang, N.X. Li, J.J. Chen, X.-P. Zhang^*, F. Liu^* and W. Wang (2018) Modulation of dynamic modes by interplay between positive and negative feedback loops in gene regulatory networks.  Phys. Rev. E 97, 042412.

B. Huang, X. Tian, F. Liu^* and W. Wang (2016) Impact of time delays on oscillatory dynamics of interlinked positive and negative feedback loops.  Phys. Rev. E 94, 052413.

B. Huang, Y. Xia, F. Liu^* and W. Wang^* (2016) Realization of tristability in a multiplicatively coupled dual-loop genetic network.  Sci. Rep. 6, 28096.

C.-H. Zhou, X.-P. Zhang^*, F. Liu^* and W. Wang (2015) Modeling the interplay between the HIF-1 and p53 pathways in hypoxia.  Sci. Rep. 5, 13834.

Q.-H. Zhang, X.-J. Tian, F. Liu^* and W. Wang^* (2014) A switch-like dynamic mechanism for the initiation of replicative senescence.  FEBS Lett. 588, 4369-4374.

X.-P. Zhang, F. Liu^* and W. Wang^* (2014) Interplay between Mdm2 and HIPK2 in the DNA damage response.  J. R. Soc. Interface 11, 20140319.

Y. Wang, F. Liu^*, J. Li and W. Wang^* (2014) Reconciling the concurrent fast and slow cycling of proteins on gene promoters.  J. R. Soc. Interface 11, 20140253.

C.-H. Zhou, X.-P. Zhang, F. Liu^* and W. Wang^* (2014) Involvement of miR-605 and miR-34a in the DNA damage response promotes apoptosis induction.  Biophys. J. 106, 1792-1800.

Y. Wang, F. Liu^* and W. Wang^* (2012) Dynamic mechanism for the transcription apparatus orchestrating reliable responses to activators.  Sci. Rep. 2, 422.

X.-P. Zhang, F. Liu^* and W. Wang^* (2012) Regulation of the DNA damage response by p53 cofactors.  Biophys. J. 102, 2251-2260.

X.-P. Zhang, F. Liu^* and W. Wang^* (2010) Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in response to DNA damage.  J. Biol. Chem. 285, 31571-31580.

T. Pu, X.-P. Zhang, F. Liu^* and W. Wang^* (2010) Coordination of the nuclear and cytoplasmic activities of p53 in response to DNA damage.  Biophys. J. 99, 1696-1705.

Z. Cheng, F. Liu^*, X.-P. Zhang and W. Wang^* (2009) Reversible phosphorylation subserves robust circadian rhythms by creating a switch in inactivating the positive element.  Biophys. J. 97, 2867-2875.

X.-J. Tian, X.-P. Zhang, F. Liu^* and W. Wang^* (2009) Interlinking positive and negative feedback loops creates a tunable motif in gene regulatory networks.  Phys. Rev. E 80, 011926.

J. Li, F. Liu^*, D. Xu and W. Wang (2009) Signal propagation through feedforward neuronal networks with different operational modes.  EPL 85, 38006.

Z. Cheng, F. Liu^*, X.-P. Zhang and W. Wang^* (2008) Robustness analysis of cellular memory in an autoactivating positive feedback system.  FEBS Lett. 582, 3776-3782.

X.-P. Zhang, Z. Cheng, F. Liu^* and W. Wang^* (2007) Linking fast and slow positive feedback loops creates an optimal bistable switch in cell signaling.  Phys. Rev. E 76, 031924.

S. Wang, W. Wang^* and F. Liu (2006) Propagation of firing rate in a feed-forward neuronal network.  Phys. Rev. Lett. 96, 018103.